Description

Methyl (2E)-3-Chloroacrylate is a high-purity, reactive α,β-unsaturated ester derivative. This compound serves as a versatile and critical building block in advanced organic synthesis, valued for its ability to introduce both an acrylate moiety and a reactive chlorine handle into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: Key synthon for the production of active pharmaceutical ingredients (APIs), particularly in the synthesis of antiviral and anticancer compounds.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where its reactive sites allow for structural diversification.
• Polymer & Resin Modifiers: Acts as a functional monomer for creating specialty polymers with enhanced properties like weather resistance, adhesion, and cross-linking capability.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for Michael addition reactions, cycloadditions, and other C-C bond-forming transformations.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized colorants and photoinitiators.
• Adhesive & Coating Formulations: Imparts durability and chemical resistance when incorporated into high-performance coating and adhesive systems.

Basic Information

Product Name	Methyl (2E)-3-Chloroacrylate
CAS No.	5135-18-2
Molecular Formula	C4H5ClO2
Molecular Weight	120.53 g/mol
Synonyms	trans-Methyl 3-chloroacrylate; Methyl trans-3-chloroacrylate; (E)-Methyl 3-chloro-2-propenoate; 3-Chloroacrylic acid methyl ester; 2-Propenoic acid, 3-chloro-, methyl ester, (2E)-; Methyl β-chloroacrylate; NSC 404087; Methyl (E)-3-chloroacrylate
EINECS	225-882-5

Quality Control

Our Methyl (2E)-3-Chloroacrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
(E)-Isomer Content	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.