Description

4-Biphenylboronic Acid is a versatile and high-value organoboron compound, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This makes it an essential reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or extended aromatic systems for therapeutic agents.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions to introduce the biphenyl moiety.
• Material Science & OLED Development: Employed in the production of organic light-emitting diodes (OLEDs), liquid crystals, and other electronic materials where controlled conjugation is required.
• Ligand & Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming methodologies and constructing molecular libraries.
• Polymer Modification: Can be incorporated into polymer backbones to alter physical properties such as thermal stability, rigidity, or electronic characteristics.

Basic Information

Product Name	4-Biphenylboronic Acid
CAS No.	5122-94-1
Molecular Formula	C12H11BO2
Molecular Weight	198.03 g/mol
Synonyms	[1,1'-Biphenyl]-4-boronic Acid; 4-Phenylphenylboronic Acid; p-Biphenylboronic Acid; (1,1'-Biphenyl-4-yl)boronic Acid; 4-Biphenylylboronic Acid; Biphenyl-4-boronic Acid; p-Biphenylylboronic Acid; 4-Boronobiphenyl
EINECS	Contact for details

Quality Control

Our 4-Biphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.