Description

5-(tert-Butyl)-2-Iodo-1,3-Dimethylbenzene is a high-purity, halogenated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, offering a reactive iodine site for cross-coupling reactions and functional group transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to create novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates requiring a sterically hindered, iodinated benzene core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators where its structural motif can impart specific biological activity.
• Material Science & Organic Electronics: Acts as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Heck couplings to form new carbon-carbon bonds.
• Ligand & Catalyst Development: Utilized to synthesize sophisticated ligands for metal complexes used in homogeneous catalysis.
• Chemical Research & Development: A valuable tool in academic and industrial labs for exploring new synthetic pathways and creating compound libraries for screening.

Basic Information

Product Name	5-(tert-Butyl)-2-Iodo-1,3-Dimethylbenzene
CAS No.	5122-20-3
Molecular Formula	C12H17I
Molecular Weight	288.17 g/mol
Synonyms	2-Iodo-5-tert-butyl-1,3-dimethylbenzene; 1-tert-Butyl-3,5-dimethyl-2-iodobenzene; 2-Iodo-1,3-dimethyl-5-(tert-butyl)benzene; 5-tert-Butyl-2-iodo-m-xylene; 2-Iodo-5-(1,1-dimethylethyl)-1,3-dimethylbenzene; 1,3-Dimethyl-5-tert-butyl-2-iodobenzene
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyl)-2-Iodo-1,3-Dimethylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.