Description

4-Methylphenyl Boronic Acid Anhydride is a high-purity organoboron reagent essential for modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages for optimal activity.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Preparation: Utilized for synthesizing specialized ligands for transition metal catalysis and other organometallic complexes.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming methodologies.
• Fine Chemical Production: Employed in the manufacture of complex dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	4-Methylphenyl Boronic Acid Anhydride
CAS No.	5084-80-0
Molecular Formula	C14H14B2O2
Molecular Weight	235.88 g/mol
Synonyms	p-Tolylboronic Anhydride; Bis(4-methylphenyl)borinic Anhydride; Di-p-tolylborinic Anhydride; 4-Methylbenzeneboronic Acid Anhydride; (4-Methylphenyl)boronic Acid Anhydride; p-Methylphenylboronic Acid Anhydride; p-Tolylboronic Acid Anhydride; Boron, tris(4-methylphenyl)-, anhydride
EINECS	Contact for details

Quality Control

Our 4-Methylphenyl Boronic Acid Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.