Description

trans-1,2-Cyclopentanediol is a versatile chiral diol building block with significant utility in organic synthesis and pharmaceutical development. Its rigid, fused-ring structure and defined stereochemistry make it a valuable precursor for constructing complex molecules, particularly in asymmetric synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, nucleoside analogs, and other bioactive molecules.
• Asymmetric Catalyst Ligand: Serves as a precursor for developing novel chiral ligands used in enantioselective catalysis.
• Polymer Chemistry: Used as a monomer or cross-linking agent to introduce rigidity and specific stereochemistry into specialty polymers.
• Agrochemical Synthesis: An intermediate in the production of chiral pesticides and herbicides.
• Flavor and Fragrance Industry: Employed in the synthesis of stereochemically defined aroma chemicals.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	trans-1,2-Cyclopentanediol
CAS No.	5057-99-8
Molecular Formula	C5H10O2
Molecular Weight	102.13 g/mol
Synonyms	(1R,2R)-1,2-Cyclopentanediol; (1S,2S)-1,2-Cyclopentanediol; trans-Cyclopentane-1,2-diol; rac-trans-1,2-Cyclopentanediol; (±)-trans-1,2-Cyclopentanediol; 1,2-Cyclopentanediol, trans-; Cyclopentanediol
EINECS	225-758-7

Quality Control

Our trans-1,2-Cyclopentanediol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We offer various grades, including standard and high-purity, to meet diverse application needs. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Specific Rotation (for chiral grades)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.