Description

1-Amino-2-Phenylcyclohexanecarboxylic Acid is a chiral, non-proteinogenic amino acid derivative featuring a cyclohexane ring system. This compound serves as a versatile and valuable pharmaceutical intermediate and building block in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-mimetic drugs and other bioactive molecules.
• Asymmetric Synthesis: Employed as a building block for constructing complex chiral ligands and organocatalysts.
• Peptidomimetics Research: Used to introduce conformational constraints and novel structural motifs into peptide analogs to enhance stability and biological activity.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme mechanisms and protein interactions.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A critical reagent for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-Amino-2-Phenylcyclohexanecarboxylic Acid
CAS No.	5034-75-3
Molecular Formula	C13H17NO2
Molecular Weight	219.28 g/mol
Synonyms	2-Phenyl-1-aminocyclohexanecarboxylic Acid; 1-Amino-2-phenylcyclohexane-1-carboxylic Acid; (1R,2S)-1-Amino-2-phenylcyclohexanecarboxylic Acid (for specific enantiomer); (1S,2R)-1-Amino-2-phenylcyclohexanecarboxylic Acid; 1-Amino-2-phenyl-cyclohexanecarboxylic acid; α-Amino-α-phenylcyclohexaneacetic acid; 2-Phenylcyclohexylaminocarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-Amino-2-Phenylcyclohexanecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiomeric grades)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.