Description

Calcium Lactobionate is a high-purity calcium salt of lactobionic acid, a versatile compound with significant utility in pharmaceutical and food science applications. Its primary value lies in its excellent chelating properties and its role as a source of bioavailable calcium, making it a critical excipient and functional ingredient. This product is essential for manufacturers in the pharmaceutical, nutraceutical, and specialty food industries seeking a reliable, high-quality ingredient for formulation stability and efficacy.

Application

• Pharmaceutical Excipient: Widely used as a stabilizer, buffer, and calcium source in injectable formulations, including intravenous (IV) solutions and lyophilized (freeze-dried) products.
• Chelating Agent: Acts as an effective metal ion chelator in ophthalmic solutions and other sensitive pharmaceutical preparations to enhance shelf-life and stability.
• Nutraceutical Ingredient: Serves as a source of bioavailable calcium in dietary supplements and fortified food products.
• Cryoprotectant: Used in the freeze-drying (lyophilization) process of biologics and sensitive pharmaceuticals to protect cell structure and protein integrity.
• Food Additive: Functions as a firming agent, stabilizer, and sequestrant in various food products, contributing to texture and quality preservation.
• Cosmetic Formulations: Incorporated into skincare products for its moisturizing and stabilizing properties.

Basic Information

Product Name	Calcium Lactobionate
CAS No.	5001-51-4
Molecular Formula	C24H42CaO24
Molecular Weight	754.66 g/mol
Synonyms	Calcium 4-O-β-D-Galactopyranosyl-D-gluconate; Lactobionic Acid Calcium Salt; D-Gluconic Acid, 4-O-β-D-Galactopyranosyl-, Calcium Salt (2:1); Calciolactobionate; Calcium Lactobionate Dihydrate (common hydrate form); E399 (when used as a food additive); NSC 11319
EINECS	225-668-6

Quality Control

Our Calcium Lactobionate is manufactured under strict quality management systems. It is typically produced to meet standards suitable for pharmaceutical and food-grade applications, with specifications aligning with industry expectations for purity and consistency. Certificates of Analysis (COA) documenting identity, assay, impurity profiles, and other critical parameters are provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. Recommended storage temperature is 15-25°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (on dried basis)	98.0% - 102.0%
pH (5% solution)	6.0 - 7.5
Loss on Drying	≤ 6.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition (Sulfated Ash)	19.0% - 21.0%
Specific Rotation [α]20/D	+22.0° to +26.0°
Microbial Limits	Meets Ph. Eur./USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.