Description

2-Bromo-2'-Chloroacetophenone is a versatile halogenated acetophenone derivative that serves as a critical building block in advanced organic synthesis. Its unique bifunctional halogenated structure makes it a valuable intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the fine chemical, pharmaceutical, and life science industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its reactive halogen sites.
• Chemical Research & Development: A valuable reagent for exploring new organic reactions and constructing heterocyclic compounds.
• Material Science: Potential building block for specialty polymers and liquid crystals.
• Cross-Coupling Reactions: Serves as an electrophile in palladium-catalyzed coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical production.

Basic Information

Product Name	2-Bromo-2'-Chloroacetophenone
CAS No.	5000-66-8
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	ω-Bromo-2'-chloroacetophenone; 2-Bromo-1-(2-chlorophenyl)ethanone; 2'-Chloro-2-bromoacetophenone; 1-(2-Chlorophenyl)-2-bromoethanone; α-Bromo-2-chloroacetophenone; (2-Chlorophenyl)(bromo)methanone; Bromo(2-chlorophenyl)methanone; NSC 404087
EINECS	Contact for details

Quality Control

Our 2-Bromo-2'-Chloroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.