Description

2,2-Dimethylsuccinic Acid is a high-purity, versatile dicarboxylic acid derivative with a unique sterically hindered structure. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis, enabling the production of complex molecules. It is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty polymer industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its hindered acid functionality.
• Polymer & Resin Modifier: Serves as a monomer or cross-linking agent to introduce steric hindrance and modify the thermal and mechanical properties of polyesters, polyamides, and epoxy resins.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical & Flavor/Fragrance Intermediate: A building block for creating complex esters and other derivatives used in high-value fine chemicals.
• Research & Development: A standard reagent in organic chemistry laboratories for method development and studying steric effects in reaction mechanisms.

Basic Information

Product Name	2,2-Dimethylsuccinic Acid
CAS No.	597-43-3
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	2,2-Dimethylbutanedioic Acid; alpha,α-Dimethylsuccinic Acid; 2,2-Dimethyl-1,4-butanedioic Acid; 2,2-Dimethylsuccinate; NSC 66400; Tetramethylsuccinic Acid (common misnomer); Dimethylsuccinic Acid (isomer unspecified); 2,2-Dimethylsuccinsäure
EINECS	209-904-6

Quality Control

Every batch of 2,2-Dimethylsuccinic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure the material meets the precise requirements for your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	140 - 145 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.