Description

2,2-Dimethyl-Acetoacetic Acid Ethyl Ester is a versatile β-keto ester derivative, valued as a key synthetic building block in organic chemistry. Its structure, featuring both a ketone and an ester functional group, makes it an essential intermediate for constructing complex molecular frameworks. This compound is particularly critical for manufacturers and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), including heterocyclic compounds and complex molecules.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and plant growth regulators, leveraging its reactivity for constructing specific bioactive cores.
• Fine Chemical Production: Serves as a building block for dyes, pigments, fragrances, and other high-value specialty chemicals.
• Academic & Industrial R&D: Employed in research laboratories for method development and the exploration of new synthetic pathways.
• Chemical Synthesis: Utilized in Claisen condensations, alkylations, and other key reactions to introduce the acetoacetate moiety into target molecules.

Basic Information

Product Name	2,2-Dimethyl-Acetoacetic Acid Ethyl Ester
CAS No.	597-04-6
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Ethyl 2,2-Dimethylacetoacetate; Ethyl 2,2-Dimethyl-3-oxobutanoate; 3-Oxobutanolic Acid, 2,2-Dimethyl-, Ethyl Ester; 2,2-Dimethyl-3-oxobutanoic Acid Ethyl Ester; Acetoacetic Acid, 2,2-Dimethyl-, Ethyl Ester; Ethyl Dimethylacetoacetate; EDAE; 597-04-6
EINECS	209-901-6

Quality Control

Our 2,2-Dimethyl-Acetoacetic Acid Ethyl Ester is manufactured under stringent quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (20°C)	0.98 - 1.02 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.