Description

Triphenylmethyl Bromide is a versatile organobromine compound widely used as a key reagent and protecting group in advanced organic synthesis. Its primary value lies in its ability to act as a robust tritylating agent, introducing the bulky triphenylmethyl (trityl) group to protect sensitive functional groups like alcohols and amines during multi-step reactions. This makes it an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the synthesis of complex molecules, nucleosides, and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for protecting hydroxyl groups in nucleoside and carbohydrate chemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where selective protection of functional groups is required.
• Polymer Chemistry: Serves as an initiator or chain-transfer agent in controlled radical polymerization processes.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other high-value specialty chemicals.
• Research & Development: A staple in organic chemistry laboratories for method development and the synthesis of novel compounds.
• Protecting Group Chemistry: Specifically for the introduction of the acid-labile trityl (Trt) group to protect alcohols, thiols, and amines.

Basic Information

Product Name	Triphenylmethyl Bromide
CAS No.	596-43-0
Molecular Formula	C19H15Br
Molecular Weight	323.23 g/mol
Synonyms	Trityl Bromide; Bromotriphenylmethane; Triphenylbromomethane; α-Bromotriphenylmethane; Trityl Bromide (Triphenylmethyl Bromide); TPM-Br; (Triphenylmethyl)bromide; NSC 406902
EINECS	209-886-9

Quality Control

Our Triphenylmethyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	150 - 154 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.