Description

(1R,3R)-1,2,2-Trimethylcyclopentane-1,3-Dicarboxylic Acid is a high-purity, stereochemically defined cyclopentane derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its rigid, functionalized structure is essential for constructing complex molecular architectures with precise stereochemical control. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those requiring specific stereochemistry for biological activity.
• Asymmetric Catalysis: Used in the development and synthesis of novel chiral ligands and organocatalysts for enantioselective reactions.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialty chemicals, fragrances, and advanced materials with tailored properties.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new chemical spaces in medicinal chemistry programs.
• Material Science Precursor: Potential use in the synthesis of monomers for specialized polymers or as a modifier for surface-active compounds.

Basic Information

Product Name	(1R,3R)-1,2,2-Trimethylcyclopentane-1,3-Dicarboxylic Acid
CAS No.	595-32-4
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(1R,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid; (1R,3R)-1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid; (1R,3R)-TMCDA; (1R,3R)-1,2,2-Trimethylcyclopentanedicarboxylic Acid; (1R,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylate; (1R,3R)-1,2,2-Trimethylcyclopentane-1,3-dioic acid; (1R,3R)-1,2,2-Trimethyl-1,3-cyclopentanedioic acid; (1R,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic acid (enantiomer)
EINECS	Contact for details

Quality Control

Our (1R,3R)-1,2,2-Trimethylcyclopentane-1,3-Dicarboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including HPLC/Chiral HPLC for purity and enantiomeric excess (ee) verification, and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.