Description

2-Methylbut-3-Yn-1-Ol is a versatile terminal alkyne alcohol, a key building block in organic synthesis. Its unique structure, featuring both a hydroxyl group and a reactive acetylene moiety, makes it an invaluable intermediate for constructing complex molecular frameworks. This compound is essential for research and industrial chemists in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce functionalized alkyne units into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring alkyne linkages for click chemistry or as structural components.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its alkyne functionality enables specific bioactivity.
• Specialty Polymer Monomer: Acts as a monomer or co-monomer for creating polymers with tailored properties, such as adhesives, coatings, and resins with enhanced thermal or mechanical characteristics.
• Organic Synthesis Building Block: Employed in Sonogashira coupling, Huisgen cycloaddition, and other cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis and organocatalysts in asymmetric synthesis.
• Fragrance and Flavor Intermediate: Functions as a starting material for synthesizing specific aroma chemicals and flavor compounds.

Basic Information

Product Name	2-Methylbut-3-Yn-1-Ol
CAS No.	584-00-9
Molecular Formula	C5H8O
Molecular Weight	84.12 g/mol
Synonyms	3-Butyn-1-ol, 2-methyl-; 2-Methyl-3-butyn-1-ol; 2-Methylbut-3-yn-1-ol; 2-Methyl-3-butynol; 3-Butyn-1-ol, 2-methyl-; 2-Methylbutynol; 2-Methyl-3-butyn-1-ol (main); 1-Hydroxy-2-methyl-3-butyne
EINECS	209-525-5

Quality Control

Our 2-Methylbut-3-Yn-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed to prevent moisture absorption and potential oxidation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.435
Density (20°C)	0.90 - 0.92 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.