Description

Diacetone-D-Glucose CAS NO 582-52-5 is a protected sugar derivative, specifically the 1,2:5,6-di-O-isopropylidene derivative of D-glucose. This compound serves as a crucial chiral building block and synthetic intermediate in organic chemistry, offering a stable, non-reducing form of glucose with protected hydroxyl groups. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, enantiomerically pure intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of nucleoside analogs, antiviral drugs, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Serves as a starting material for synthesizing complex carbohydrates, glycosides, and other specialty chemicals.
• Academic & Research: A standard reagent in carbohydrate chemistry research, asymmetric synthesis, and methodological development.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of certain sugar-derived aroma compounds.
• Material Science: Can be utilized in the development of chiral polymers or functionalized surfaces.

Basic Information

Product Name	Diacetone-D-Glucose
CAS No.	582-52-5
Molecular Formula	C12H20O6
Molecular Weight	260.28 g/mol
Synonyms	1,2:5,6-Di-O-Isopropylidene-α-D-glucofuranose; Diacetoneglucose; 1,2:5,6-Di-O-isopropylidene-D-glucofuranose; D-Glucose Diethyl Acetal; Diacetone-D-glucofuranose; Isopropylidene-D-glucose; Diacetone Glucose; 1,2:5,6-Diisopropylidene-D-glucofuranose
EINECS	209-475-6

Quality Control

Our Diacetone-D-Glucose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and consistent performance. We provide detailed Certificates of Analysis (COA) that include data for identity, assay, optical rotation, and impurity profiles, supporting its use in regulated applications. Specifications can be aligned with customer requirements for research or commercial-scale projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.