Description

3,3'-Bis(Trifluoromethyl)-1,1'-Biphenyl is a high-value, fluorinated biphenyl derivative characterized by its unique chemical structure. This compound is prized for its role as a critical building block in advanced organic synthesis, particularly in the development of specialty materials and pharmaceuticals. It is essential for researchers and manufacturers in the agrochemical, pharmaceutical, and advanced materials sectors who require precise, high-purity intermediates for complex syntheses.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial precursor for developing novel herbicides, fungicides, and insecticides, where the CF3 groups contribute to lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its rigid, fluorinated biphenyl core influences mesomorphic and electronic properties.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to create high-performance polymers with improved chemical resistance, thermal stability, and low surface energy.
• Ligand & Catalyst Development: Acts as a backbone for constructing sophisticated ligands in catalysis, particularly in cross-coupling and asymmetric synthesis.
• Advanced Material Research: Employed in academic and industrial R&D for exploring new fluorinated aromatic compounds with tailored electronic and physical characteristics.

Basic Information

Product Name	3,3'-Bis(Trifluoromethyl)-1,1'-Biphenyl
CAS No.	580-82-5
Molecular Formula	C14H8F6
Molecular Weight	290.21 g/mol
Synonyms	3,3'-Bis(trifluoromethyl)biphenyl; 1,1'-Biphenyl, 3,3'-bis(trifluoromethyl)-; 3,3'-(Biphenyl-1,1'-diyl)bis(trifluoromethyl)benzene; 3,3'-Di(trifluoromethyl)biphenyl; 3,3'-Bis(trifluoromethyl)diphenyl; α,α,α,α',α',α'-Hexafluoro-3,3'-dimethylbiphenyl; Biphenyl, 3,3'-bis(trifluoromethyl)-; 580-82-5
EINECS	Contact for details

Quality Control

Our 3,3'-Bis(Trifluoromethyl)-1,1'-Biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.