Description

5'-Fluoro-2'-Hydroxybutyrophenone is a specialized fluorinated aromatic ketone, serving as a valuable intermediate in advanced organic synthesis. Its molecular structure, featuring both a fluorine substituent and a hydroxyl group, makes it a versatile building block for creating more complex molecules with tailored properties. This compound is particularly relevant for research and development chemists in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a key strategy for modulating bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and lighting.
• Advanced Polymer Chemistry: Employed to introduce fluorinated side chains into polymers, modifying their surface properties, chemical resistance, and stability.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.
• Fluorine Chemistry Studies: Used as a model compound in academic and industrial research exploring new fluorination reactions and methodologies.

Basic Information

Product Name	5'-Fluoro-2'-Hydroxybutyrophenone
CAS No.	575-67-7
Molecular Formula	C10H11FO2
Molecular Weight	182.19 g/mol
Synonyms	1-(5-Fluoro-2-hydroxyphenyl)-1-butanone; 5-Fluoro-2-hydroxybutyrophenone; 1-Butanone, 1-(5-fluoro-2-hydroxyphenyl)-; 2-Hydroxy-5-fluorobutyrophenone; 5-Fluoro-2'-hydroxybutyrophenone; 5-Fluoro-2-hydroxybutyrophenone; 5-Fluoro-2'-hydroxybutyrophenone (alternative punctuation)
EINECS	Contact for details

Quality Control

Our 5'-Fluoro-2'-Hydroxybutyrophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.