Description

Euphorbol CAS NO 566-14-3 is a diterpenoid compound belonging to the tigliane class, structurally related to phorbol esters. This compound is of significant interest in biochemical and pharmacological research due to its role as a key structural analog and precursor in the study of protein kinase C (PKC) modulation. It serves as a critical intermediate for researchers and developers in the life sciences sector, particularly those investigating signal transduction pathways, tumor promotion, and novel therapeutic agents. Its defined structure makes it a valuable reference standard and building block for specialized synthetic applications.

Application

• Biochemical Research: Used as a reference standard and probe in studies of protein kinase C (PKC) activation and related signal transduction mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or precursor in the synthesis of novel compounds for oncology and inflammation research.
• Toxicology Studies: Employed as a model compound to investigate the biological activity and mechanisms of phorbol ester-related tumor promotion.
• Academic Research: Utilized in university and institutional labs for fundamental research in natural product chemistry and medicinal chemistry.
• Standards and Metrology: Acts as a high-purity certified reference material (CRM) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	Euphorbol
CAS No.	566-14-3
Molecular Formula	C20H30O5
Molecular Weight	350.45 g/mol
Synonyms	Euphorbol; 12-Deoxy-16-hydroxyphorbol; (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(Hydroxymethyl)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b,9-trihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9-yl acetate; 12-Deoxy-16-hydroxyphorbol; NSC 169925
EINECS	Contact for details

Quality Control

Our Euphorbol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). We provide full traceability and detailed Certificates of Analysis (COA) upon request, supporting compliance with rigorous laboratory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.