Description

cis-4-Hydroxy-Alpha,Alpha,4-Trimethylcyclohexanemethanol is a high-purity, functionalized cyclohexane derivative with significant utility in advanced organic synthesis. This compound matters as a versatile chiral building block and intermediate, prized for its defined stereochemistry and hydroxyl functionality which enable the construction of complex molecular architectures. It is needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty fragrance industries for applications ranging from active pharmaceutical ingredient (API) synthesis to the development of novel performance chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of sterically hindered, biologically active molecules and potential APIs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for musky, woody, or amber odorants due to its complex, polycyclic structure.
• Polymer & Resin Modifier: The hydroxyl group allows for incorporation into polymer chains, modifying properties like flexibility, adhesion, or cross-linking density.
• Liquid Crystal & Electronic Materials: Acts as a core or side-chain component in the design of specialty organic materials for displays and optoelectronics.
• Asymmetric Catalysis Ligand Precursor: Utilized in the development of novel chiral ligands for catalytic asymmetric transformations.

Basic Information

Product Name	cis-4-Hydroxy-Alpha,Alpha,4-Trimethylcyclohexanemethanol
CAS No.	565-48-0
Molecular Formula	C11H22O2
Molecular Weight	186.29 g/mol
Synonyms	cis-4-Hydroxy-α,α,4-trimethylcyclohexanemethanol; 4-Hydroxy-α,α,4-trimethyl-1-cyclohexanemethanol (cis-); (1R,4S)-4-Hydroxy-α,α,4-trimethylcyclohexanemethanol; 1,4-Cyclohexanedimethanol, 4-hydroxy-α,α,4-trimethyl-, cis-; Hydroxytrimethylcyclohexanemethanol; Cyclohexanemethanol, 4-hydroxy-α,α,4-trimethyl-, cis-; Dihydro Homocarveol (related isomer)
EINECS	209-274-4

Quality Control

Our cis-4-Hydroxy-Alpha,Alpha,4-Trimethylcyclohexanemethanol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.