Description

11-Deoxo-18Beta-Glycyrrhetic Acid is a high-purity, semi-synthetic derivative of glycyrrhetinic acid, a key bioactive triterpenoid from licorice root. This compound is valued for its enhanced pharmacological profile and serves as a crucial intermediate in the synthesis of advanced pharmaceutical and cosmetic ingredients. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and high-end personal care industries for developing anti-inflammatory, hepatoprotective, and skin-conditioning formulations.

Application

• Pharmaceutical Intermediate: Key starting material for synthesizing potent anti-inflammatory and antiviral drugs, including improved glycyrrhetinic acid derivatives.
• Cosmetic & Skincare Actives: Used in formulations for its skin-soothing, anti-irritant, and whitening properties, often found in serums, creams, and lotions.
• Nutraceutical Supplements: Incorporated into dietary supplements for potential liver support and digestive health benefits.
• Biochemical Research: Serves as a reference standard and reagent in pharmacological and metabolic pathway studies.
• Veterinary Medicine: Used in developing therapeutic preparations for animal health.

Basic Information

Product Name	11-Deoxo-18Beta-Glycyrrhetic Acid
CAS No.	564-16-9
Molecular Formula	C30H46O4
Molecular Weight	470.69 g/mol
Synonyms	11-Deoxoglycyrrhetic Acid; 11-Deoxo-18β-Glycyrrhetinic Acid; 18β-Glycyrrhetinic Acid 11-Deoxo Derivative; 3β-Hydroxy-11-oxoolean-12-en-30-oic Acid (related); Enoxolone Derivative; (20β)-3-Hydroxy-11-oxoolean-12-en-29-oic Acid; UR-1377 (research code); Licorice Triterpenoid Derivative
EINECS	Contact for details

Quality Control

Our 11-Deoxo-18Beta-Glycyrrhetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets stringent specifications for pharmaceutical and cosmetic applications. Certificates of Analysis (COA) are provided with every shipment, and we can support compliance with GMP, ICH Q7 guidelines, and REACH requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.