Description

Columbin is a naturally occurring sesquiterpene lactone compound, identified by CAS No. 546-97-4. This bioactive molecule is of significant interest for its potential physiological effects and serves as a key intermediate in advanced organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for development and production purposes.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) intermediate for investigating novel therapeutic agents.
• Natural Product Isolation & Standardization: Used as a marker compound for the quality control and standardization of botanical extracts.
• Biochemical & Pharmacological Studies: Employed in in-vitro and in-vivo studies to explore its biological activity and mechanism of action.
• Fine Chemical Synthesis: Serves as a sophisticated chiral building block for the synthesis of complex organic molecules.
• Academic Research: Utilized in university and institutional labs for chemical education and advanced organic chemistry projects.

Basic Information

Product Name	Columbin
CAS No.	546-97-4
Molecular Formula	C20H22O7
Molecular Weight	374.38 g/mol
Synonyms	Columbin; (3aS,6aR,9aS,9bR)-9-(Furan-3-yl)-3a,4,5,8,9,9a-hexahydro-3H-3a,6a-epoxybenzofuro[3,2-c]isobenzofuran-1,7-dione; Jateorin; 6H-Furo[3,2-c:5,4-c']difuran-1,7-dione, 9-(3-furanyl)-3a,4,5,8,9,9a-hexahydro-3a,6a-epoxy-, (3aS,6aR,9aS,9bR)-; NSC 169854
EINECS	Contact for details

Quality Control

Our Columbin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support research and industrial applications by providing material that meets stringent in-house specifications, with the capability to align with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.