Description

3-Chloro-4-Fluorobutanoic Acid Methyl Ester is a versatile fluorinated organic building block of significant importance in advanced chemical synthesis. Its unique structure, featuring both chloro and fluoro substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Material Precursor: Serves as a starting material for fluorinated liquid crystal compounds used in display technologies.
• Organic Synthesis Building Block: Employed in nucleophilic substitution and coupling reactions to introduce functionalized butanoate chains into target molecules.
• Polymer Modification Agent: Utilized to incorporate halogenated side chains into polymers, altering their physical and chemical resistance properties.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and creating novel fluorinated compounds in R&D laboratories.

Basic Information

Product Name	3-Chloro-4-Fluorobutanoic Acid Methyl Ester
CAS No.	541-86-6
Molecular Formula	C5H8ClFO2
Molecular Weight	154.57 g/mol
Synonyms	Methyl 3-Chloro-4-fluorobutanoate; 4-Fluoro-3-chlorobutanoic Acid Methyl Ester; Butanoic acid, 3-chloro-4-fluoro-, methyl ester; 3-Chloro-4-fluorobutyric acid methyl ester; Methyl 4-fluoro-3-chlorobutyrate; 541-86-6; Methyl 3-chloro-4-fluorobutyrate
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Fluorobutanoic Acid Methyl Ester adheres to stringent quality management protocols. Each batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 2°C and 8°C for extended stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.425 - 1.435
Density	1.25 - 1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.