Description

1,1,1-Trifluoro-3-Iodobutane is a versatile fluorinated and iodinated organic building block. This compound is valued for its unique reactivity, where the iodine atom serves as an excellent leaving group for nucleophilic substitution, and the trifluoromethyl group imparts desirable properties like enhanced lipophilicity and metabolic stability. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for introducing the trifluoromethyl group into potential drug candidates, particularly in medicinal chemistry for CNS and oncology targets.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the CF3 group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated components used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Negishi, Stille) to form new carbon-carbon bonds.
• Fluorinated Surfactant & Polymer Research: Employed in R&D for creating specialty surfactants and polymers with unique surface properties and chemical resistance.
• Radiolabeling & Tracer Studies: The iodine atom provides a potential site for radioiodination (e.g., with I-125) for use in diagnostic imaging and biochemical research.

Basic Information

Product Name	1,1,1-Trifluoro-3-Iodobutane
CAS No.	540-87-4
Molecular Formula	C4H6F3I
Molecular Weight	237.99 g/mol
Synonyms	3-Iodo-1,1,1-trifluorobutane; 1,1,1-Trifluoro-3-iodobutane; Butane, 1,1,1-trifluoro-3-iodo-; 3-Iodobutyl trifluoride; 1-Iodo-3-trifluoromethylpropane
EINECS	Contact for details

Quality Control

Every batch of 1,1,1-Trifluoro-3-Iodobutane is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C to maximize shelf life and stability. Keep container tightly sealed when not in use to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.