Description

1,4-Difluorobenzene is a versatile fluorinated aromatic compound, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity imparted by the fluorine atoms, making it an essential intermediate for high-performance materials and active pharmaceutical ingredients. This product is primarily needed by manufacturers in the agrochemical, pharmaceutical, and specialty polymer industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing fluorinated aromatic rings.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where fluorine substitution improves efficacy and environmental stability.
• Liquid Crystal Materials: Serves as a fundamental building block for fluorinated liquid crystals used in display technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers, such as polyarylates and polyetherketones, to enhance thermal stability, chemical resistance, and dielectric properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to introduce the 1,4-difluorophenyl moiety into complex molecules.
• Solvent & Reaction Medium: Functions as a specialty solvent in certain fluorination reactions and electrochemical processes.

Basic Information

Product Name	1,4-Difluorobenzene
CAS No.	540-36-3
Molecular Formula	C6H4F2
Molecular Weight	114.09 g/mol
Synonyms	p-Difluorobenzene; 1,4-Difluorobenzol; Benzene, 1,4-difluoro-; Difluorobenzene (para); 4-Fluorophenyl fluoride; Flerobenzen; NSC 9237; UN 1993
EINECS	208-757-8

Quality Control

Our 1,4-Difluorobenzene is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR), to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing assay, identity, and impurity profiles to meet the stringent requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 1.0%
Density at 20°C	1.17 - 1.18 g/mL
Boiling Point	88 - 90°C
Refractive Index (n20D)	1.440 - 1.444

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.