Description

4-Chloro-2'-Bromoacetophenone is a versatile halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, where both the chloro and bromo substituents can be selectively modified, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, where its halogen atoms facilitate further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers with specific optical or electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and protein interactions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in novel synthetic route exploration.

Basic Information

Item	Details
Product Name	4-Chloro-2'-Bromoacetophenone
CAS No.	536-38-9
Molecular Formula	C8H6BrClO
Molecular Weight	233.49 g/mol
Synonyms	2-Bromo-4'-chloroacetophenone; 1-(2-Bromophenyl)-2-chloroethanone; 2-Bromo-1-(4-chlorophenyl)ethanone; 4'-Chloro-2-bromoacetophenone; p-Chloro-2-bromoacetophenone; α-Chloro-2-bromoacetophenone; NSC 406908
EINECS	208-627-1

Quality Control

Our 4-Chloro-2'-Bromoacetophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.