Description

(+)-Methynolide CAS NO 534-32-7 is a high-purity, enantiomerically pure macrolide compound of significant interest in advanced organic synthesis and pharmaceutical research. Its defined stereochemistry and complex lactone structure make it a valuable chiral building block and a key intermediate for the development of novel bioactive molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-quality, stereochemically defined intermediates for complex synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of complex macrolide antibiotics and other therapeutic agents.
• Organic Synthesis Building Block: Used in stereoselective synthesis, including asymmetric cyclization and coupling reactions, to construct complex molecular architectures.
• Agrochemical Research: Employed in the development of novel, biologically active compounds with potential insecticidal or fungicidal properties.
• Academic & R&D Laboratories: A valuable tool for methodological studies in total synthesis, catalysis, and medicinal chemistry.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.

Basic Information

Product Name	(+)-Methynolide
CAS No.	534-32-7
Molecular Formula	C16H26O5
Molecular Weight	298.37 g/mol
Synonyms	(+)-Methynolide; (3R,5R,6R,8R,9S,10S,11S,12S,13S,14S)-3-[(2S,4S,5S,6S)-4-(Dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-5,9-dimethyoxacyclotetradecane-2,10-dione; Methynolide; NSC 326223; Antibiotic T 2636 C; T 2636 C
EINECS	Contact for details

Quality Control

Our (+)-Methynolide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity verification by HPLC, to support your critical research and development needs. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for every batch upon request, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.