Description

o-Tolunitrile is a versatile aromatic nitrile derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactive nitrile group and methyl-substituted benzene ring, enabling the construction of complex molecules for pharmaceuticals and agrochemicals. This intermediate is essential for manufacturers in the fine chemical, pharmaceutical, and specialty chemical industries seeking reliable, high-purity raw materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with ortho-substituted aromatic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the o-tolyl moiety is required.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized dyes and organic pigments.
• Ligand and Catalyst Preparation: Utilized in the development of novel ligands for metal-catalyzed cross-coupling reactions.
• Fine Chemical Production: Intermediate for producing benzoic acid derivatives, aldehydes, and amides via hydrolysis or reduction.
• Research and Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways.

Basic Information

Product Name	o-Tolunitrile
CAS No.	529-19-1
Molecular Formula	C8H7N
Molecular Weight	117.15 g/mol
Synonyms	2-Methylbenzonitrile; ortho-Tolunitrile; 2-Cyanotoluene; o-Toluonitrile; o-Methylbenzonitrile; 2-Tolyl cyanide; Benzonitrile, 2-methyl-; NSC 9245
EINECS	208-458-5

Quality Control

Our o-Tolunitrile is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory documentation requests.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	0.995 - 1.005 g/mL
Refractive Index (n20D)	1.525 - 1.535

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.