Description

2-Hydroxy-3-[(E)-4-Hydroxy-3-Methyl-2-Butenyl]-1,4-Naphthoquinone is a naturally occurring naphthoquinone derivative with significant biological activity. This compound matters for its role as a key intermediate in the synthesis of vitamin K analogs and other bioactive molecules. It is needed by research institutions, pharmaceutical manufacturers, and fine chemical producers focused on developing new therapeutic agents and studying redox biochemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of vitamin K and its analogs, as well as other naphthoquinone-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of oxidative stress, electron transport, and quinone biochemistry.
• Fine Chemical Synthesis: Serves as a versatile precursor for the development of novel organic compounds with potential biological activities.
• Cosmetic & Personal Care Ingredients: Investigated for use in formulations where antioxidant properties are desired, subject to regulatory approval.
• Agrochemical Research: Explored as a lead compound or intermediate for developing new plant growth regulators or protective agents.

Basic Information

Product Name	2-Hydroxy-3-[(E)-4-Hydroxy-3-Methyl-2-Butenyl]-1,4-Naphthoquinone
CAS No.	523-34-2
Molecular Formula	C₁₅H₁₄O₄
Molecular Weight	258.27 g/mol
Synonyms	Lapachol; 2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone; Tecomin; Greenhartin; NSC 11905; (E)-2-Hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl)naphthalene-1,4-dione; 1,4-Naphthoquinone, 2-hydroxy-3-(3-methyl-2-butenyl)-
EINECS	208-352-7

Quality Control

Our 2-Hydroxy-3-[(E)-4-Hydroxy-3-Methyl-2-Butenyl]-1,4-Naphthoquinone is produced under strict quality management systems. Products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	139 - 141 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.