Description

Diazoacetic Acid is a versatile and highly reactive organic compound, primarily recognized for its role as a key synthon in the construction of complex molecular frameworks. Its value lies in its ability to act as a carbene precursor and a 1,3-dipole, enabling critical carbon-carbon and carbon-heteroatom bond-forming reactions. This makes it an indispensable reagent for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to synthesize active ingredients and advanced intermediates.

Application

• Pharmaceutical Synthesis: A crucial building block for the preparation of heterocyclic compounds, β-lactams, and other complex bioactive molecules.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, and specialty polymers requiring specific functional groups.
• Academic & Industrial R&D: Employed in method development and catalysis research, particularly in cyclopropanation and cycloaddition reactions.
• Peptide Modification: Can be used for the site-specific functionalization of amino acids and peptides.

Basic Information

Product Name	Diazoacetic Acid
CAS No.	503-68-4
Molecular Formula	C2H2N2O2
Molecular Weight	86.05 g/mol
Synonyms	Diazoethanoic Acid; Diazoacetic Acid Ethyl Ester Precursor; N2CHCOOH; Acetic acid, diazo-; Ethyl Diazoacetate Hydrolysis Product; Carboxymethyldiazonium; Diazonium acetate
EINECS	207-968-2

Quality Control

Our Diazoacetic Acid is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. We employ advanced analytical techniques including HPLC, NMR, and IR spectroscopy for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its light-sensitive and potentially unstable nature, it is recommended to store at temperatures between 2°C and 8°C for extended stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline solid or solution
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.