Description

3-Hydroxy-3-Methylglutaric Acid is a versatile dicarboxylic acid derivative that serves as a key intermediate in the synthesis of valuable compounds. Its bifunctional structure, containing both hydroxyl and carboxylic acid groups, makes it a crucial building block for pharmaceutical and fine chemical manufacturing. This high-purity intermediate is essential for producers in the pharmaceutical, nutraceutical, and specialty chemical sectors seeking reliable and consistent raw materials for their synthesis processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of HMG-CoA reductase inhibitors, including statin drugs like lovastatin and pravastatin.
• Biochemical Research: Used as a substrate or intermediate in enzymatic studies and metabolic pathway research, particularly related to cholesterol biosynthesis.
• Fine Chemical Synthesis: Serves as a chiral building block for the production of complex organic molecules, flavors, and fragrances.
• Nutraceutical Production: Employed in the manufacture of dietary supplements, including the production of coenzyme Q10 (CoQ10) and other bioactive compounds.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the synthesis of biodegradable polyesters and other functional polymers.

Basic Information

Product Name	3-Hydroxy-3-Methylglutaric Acid
CAS No.	503-49-1
Molecular Formula	C6H10O5
Molecular Weight	162.14 g/mol
Synonyms	3-Hydroxy-3-methylpentanedioic acid; 3-Methyl-3-hydroxypentanedioic acid; HMG Acid; β-Hydroxy-β-methylglutaric acid; Mevalonic acid precursor; HMGA; 503-49-1; NSC 30223
EINECS	207-975-3

Quality Control

Our 3-Hydroxy-3-Methylglutaric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Recommended storage temperature is between 15°C and 25°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.