Description

Phenyl Trifluoroacetate is a versatile trifluoroacetylating reagent and a key synthetic intermediate in organic chemistry. Its primary value lies in its ability to introduce the trifluoroacetyl group, a moiety that can significantly alter the physical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to create novel compounds with enhanced stability, bioavailability, or specific electronic characteristics.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethyl group for metabolic stability or lipophilicity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoroacetyl group contributes to efficacy and environmental profile.
• Peptide Chemistry: Serves as a protecting group for amino groups during peptide synthesis, offering stability under various reaction conditions.
• Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials that benefit from fluorine incorporation.
• Laboratory Reagent: Utilized as a derivatization agent in analytical chemistry and as a versatile reagent for academic and industrial R&D in organic synthesis.
• Fluorine Chemistry Research: A fundamental reagent for exploring new methodologies in fluoroorganic chemistry and creating novel fluorinated compounds.

Basic Information

Product Name	Phenyl Trifluoroacetate
CAS No.	500-73-2
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	Trifluoroacetic Acid Phenyl Ester; Phenyl Trifluoroethanoate; Benzenol, Trifluoroacetate; Phenol Trifluoroacetate; Trifluoroacetyl Phenyl Ester; Phenyl Ester of Trifluoroacetic Acid; α,α,α-Trifluoroacetic Acid Phenyl Ester
EINECS	207-911-0

Quality Control

Our Phenyl Trifluoroacetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (IR, NMR), to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.