Description

1-Cyclobutyl-1H-Pyrazol-5-Amine is a high-value, nitrogen-containing heterocyclic building block with the CAS registry number 497947-61-2. This compound is essential for medicinal chemistry research and development, serving as a versatile scaffold for constructing novel pharmacologically active molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of new drug candidates, particularly in areas targeting central nervous system disorders and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates for various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Ligand Synthesis for Catalysis: Can be employed in the preparation of specialized ligands for transition metal catalysis.
• Material Science Research: Investigated as a monomer or functional additive in the development of advanced polymeric materials.

Basic Information

Product Name	1-Cyclobutyl-1H-Pyrazol-5-Amine
CAS No.	497947-61-2
Molecular Formula	C7H11N3
Molecular Weight	137.18 g/mol
Synonyms	5-Amino-1-cyclobutyl-1H-pyrazole; 1-Cyclobutyl-1H-pyrazol-5-amine; 1-Cyclobutyl-5-aminopyrazole; 1H-Pyrazol-5-amine, 1-cyclobutyl-; 497947-61-2; 5-Amino-1-cyclobutylpyrazole; Cyclobutylpyrazolamine
EINECS	Contact for details

Quality Control

Our 1-Cyclobutyl-1H-Pyrazol-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.