Description

(S)-Boroala-(-)-Pinanediol CAS NO 497165-13-6 is a high-purity, chiral boronic ester derivative used as a critical intermediate in asymmetric synthesis. This compound matters for its role in facilitating stereoselective carbon-carbon bond formation, enabling the production of enantiomerically pure pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling and other boronic acid-mediated reactions.
• Asymmetric Catalysis: Employed as a chiral auxiliary or ligand precursor in transition metal-catalyzed reactions to induce enantioselectivity.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for creating chiral organic frameworks, polymers, and liquid crystals with specific optical properties.
• Academic & Process R&D: A valuable reagent for methodological development in organic synthesis and scaling up chiral synthetic routes.
• Fine Chemical Production: Integral to the manufacture of high-value, complex chiral molecules for flavors, fragrances, and electronic chemicals.

Basic Information

Product Name	(S)-Boroala-(-)-Pinanediol
CAS No.	497165-13-6
Molecular Formula	C₁₅H₂₅BO₂
Molecular Weight	248.17 g/mol
Synonyms	(S)-(-)-Pinanediol (2-Methyl-1,3,2-dioxaborolan-2-yl)acetate; (S)-BoroAla Pinanediol Ester; (S)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)alanine Pinanediol Ester; (S)-Boroalanine Pinanediol Ester; (S)-Boro-Ala(Pin); Boro-L-alanine pinanediol ester; (S)-α-Amino boronic acid pinanediol ester (alanine derivative); (S)-1-(Pinanediolato)boryl-2-aminopropane
EINECS	Contact for details

Quality Control

Our (S)-Boroala-(-)-Pinanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chiral purity and assay, NMR for structural confirmation, and residual solvent analysis to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.