Description

2-(1,3-Benzoxazol-2-Yl)-3-(4-Fluorophenyl)-1-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture designed for targeted synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. Pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers need this precise intermediate to drive forward their discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory pathways, or oncological applications.
• Agrochemical Research: Serves as a core structure for developing new-generation pesticides or herbicides, leveraging the benzoxazole and fluorophenyl moieties for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Potential use as an electron-transporting or emissive layer material in OLED devices due to its conjugated system and structural rigidity.
• Material Science: Investigation as a monomer or additive for advanced polymers and coatings requiring specific optical or electronic properties.
• Academic & Industrial R&D: Used in chemical research for studying structure-activity relationships (SAR), reaction mechanisms, and as a reference standard.
• Fluorescent Probe Development: Exploration in the design of fluorescent dyes or sensors, utilizing its inherent fluorophore characteristics.

Basic Information

Product Name	2-(1,3-Benzoxazol-2-Yl)-3-(4-Fluorophenyl)-1-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One
CAS No.	496011-80-4
Molecular Formula	C25H20FNO5
Molecular Weight	433.43 g/mol
Synonyms	2-Propen-1-one, 2-(1,3-benzoxazol-2-yl)-3-(4-fluorophenyl)-1-(3,4,5-trimethoxyphenyl)-; (E)-2-(Benzoxazol-2-yl)-3-(4-fluorophenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one; (E)-1-(3,4,5-Trimethoxyphenyl)-3-(4-fluorophenyl)-2-(1,3-benzoxazol-2-yl)prop-2-en-1-one; 2-(Benzoxazol-2-yl)-3-(4-fluorophenyl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one; CAS 496011-80-4; Benzoxazole propenone derivative; 4-Fluorophenyl benzoxazolyl trimethoxyphenyl propenone
EINECS	Contact for details

Quality Control

Our 2-(1,3-Benzoxazol-2-Yl)-3-(4-Fluorophenyl)-1-(3,4,5-Trimethoxyphenyl)-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Single Maximum Impurity (HPLC)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.