Description

3-Bromo-4-Ethoxy-5-Methoxy-Benzonitrile is a high-purity, multi-functional benzonitrile derivative characterized by its bromo, ethoxy, and methoxy substituents, making it a versatile synthetic building block. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for its utility as a key intermediate in the synthesis of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials due to its substituted benzonitrile core.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce functionalized aromatic units.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where bromine and ether groups modify color and stability properties.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	3-Bromo-4-Ethoxy-5-Methoxy-Benzonitrile
CAS No.	495396-35-5
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	3-Bromo-4-ethoxy-5-methoxybenzonitrile; 4-Ethoxy-3-bromo-5-methoxybenzonitrile; Benzonitrile, 3-bromo-4-ethoxy-5-methoxy-; 5-Methoxy-4-ethoxy-3-bromobenzonitrile; 3-Bromo-4-ethoxy-5-methoxy-phenyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Ethoxy-5-Methoxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.