Description

1-(3-Bromophenyl)-4-Chloro-1-Oxobutane is a high-purity, specialized organic intermediate featuring both bromo and chloro substituents on an aromatic ketone backbone. This compound is valued for its versatility as a key building block in advanced synthetic chemistry, enabling the construction of complex molecular architectures. It is primarily sought by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialized polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein-ligand interactions.
• Cross-Coupling Reactions: The bromophenyl moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.
• Fine Chemical Production: Utilized in multi-step synthetic routes for producing complex fragrance compounds, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	1-(3-Bromophenyl)-4-Chloro-1-Oxobutane
CAS No.	494863-34-2
Molecular Formula	C10H10BrClO
Molecular Weight	261.54 g/mol
Synonyms	4-Chloro-1-(3-bromophenyl)butan-1-one; 3'-Bromo-4-chlorobutyrophenone; 1-(3-Bromophenyl)-4-chlorobutan-1-one; γ-Chloro-3'-bromopropiophenone; 4-Chloro-1-(3-bromophenyl)-1-butanone; 3-Bromophenyl 4-chlorobutyl ketone; Butan-1-one, 1-(3-bromophenyl)-4-chloro-
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenyl)-4-Chloro-1-Oxobutane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.