Description

Cyclohexanecarboxylic Acid, 1,3,4-Trihydroxy-5-(Hydroxyimino)-, Methyl Ester, (1S,3R,4R,5E)- (9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block in the development of complex, biologically active molecules, offering precise control over molecular architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, agrochemicals, and other fine chemicals where specific stereochemistry is critical for function.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of potential active pharmaceutical ingredients (APIs), particularly for complex natural product analogs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators that require specific stereoisomers for optimal efficacy.
• Chemical Biology & Probe Development: Acts as a scaffold or precursor for creating molecular probes to study enzyme mechanisms or biological pathways.
• Asymmetric Synthesis Catalyst Ligand Precursor: Provides a structurally complex framework for the development of novel chiral ligands used in catalytic asymmetric reactions.
• Academic & Industrial R&D: Employed in methodological research and process chemistry for constructing challenging polyfunctionalized cyclohexane rings.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals for advanced material science applications.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 1,3,4-Trihydroxy-5-(Hydroxyimino)-, Methyl Ester, (1S,3R,4R,5E)- (9Ci)
CAS No.	494211-81-3
Molecular Formula	C9H13NO6
Molecular Weight	231.20 g/mol
Synonyms	(1S,3R,4R,5E)-1,3,4-Trihydroxy-5-(hydroxyimino)cyclohexanecarboxylic acid methyl ester; Methyl (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(hydroxyimino)cyclohexanecarboxylate; (1S,3R,4R,5E)-Methyl 1,3,4-trihydroxy-5-(hydroxyimino)cyclohexanecarboxylate; 5-(Hydroxyimino)-1,3,4-trihydroxycyclohexanecarboxylic acid methyl ester, (1S,3R,4R,5E)-; CAS 494211-81-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Cyclohexanecarboxylic Acid, 1,3,4-Trihydroxy-5-(Hydroxyimino)-, Methyl Ester, (1S,3R,4R,5E)- (9Ci) is characterized and verified to meet strict purity and stereochemical specifications. Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profiles are available upon request. We adhere to cGMP principles for the manufacture of materials intended for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (1S,3R,4R,5E)-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.