Description

2H-Thiopyran-4-Carboxaldehyde, Tetrahydro-, 1,1-Dioxide is a high-purity, specialized sulfone derivative characterized by its reactive aldehyde functional group. This compound serves as a valuable and versatile advanced pharmaceutical intermediate and organic synthesis building block for constructing complex molecular architectures. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce novel sulfone-containing motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its polar sulfone group and reactive aldehyde.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2H-Thiopyran-4-Carboxaldehyde, Tetrahydro-, 1,1-Dioxide
CAS No.	494210-61-6
Molecular Formula	C6H10O3S
Molecular Weight	162.21 g/mol
Synonyms	Tetrahydro-2H-thiopyran-4-carbaldehyde 1,1-dioxide; 1,1-Dioxo-tetrahydro-2H-thiopyran-4-carboxaldehyde; 4-Formyltetrahydro-2H-thiopyran 1,1-dioxide; Tetrahydro-2H-thiopyran-4-carbaldehyde S,S-dioxide; 1,1-Dioxo-perhydro-2H-thiopyran-4-carboxaldehyde; THTP-4-CHO dioxide; Sulfolane-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2H-Thiopyran-4-Carboxaldehyde, Tetrahydro-, 1,1-Dioxide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.