Description

2,3-Dibromobenzotrifluoride is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine substituents and a trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and physical properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries to introduce fluorinated aromatic motifs, which are key to modulating bioactivity, stability, and material characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic rings that enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), influencing charge transport and emission properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Cross-Coupling Reactions: The bromine atoms serve as excellent handles for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Ligand & Catalyst Development: Utilized in the preparation of novel fluorinated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,3-Dibromobenzotrifluoride
CAS No.	493038-92-9
Molecular Formula	C7H3Br2F3
Molecular Weight	312.90 g/mol
Synonyms	1,2-Dibromo-3-(trifluoromethyl)benzene; 2,3-Dibromo-α,α,α-trifluorotoluene; 2,3-Dibromo(trifluoromethyl)benzene; Benzene, 1,2-dibromo-3-(trifluoromethyl)-; α,α,α-Trifluoro-2,3-dibromotoluene
EINECS	Contact for details

Quality Control

Our 2,3-Dibromobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and GC-MS, NMR (1H, 19F, 13C) for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~2.1 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.