Description

2-Bromo-1,5-difluoro-3-methoxybenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides leveraging its halogen and fluorine motifs.
• Liquid Crystal Materials (LCM): Serves as a core building block for fluorine-containing liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Employed in the synthesis of semiconductors and charge-transport materials for OLEDs and other electronic devices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl systems.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing complex aromatic systems in academic and industrial labs.

Basic Information

Product Name	2-Bromo-1,5-Difluoro-3-Methoxybenzene
CAS No.	491852-44-9
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	1-Bromo-2,6-difluoro-4-methoxybenzene; 3-Bromo-2,6-difluoroanisole; 2,6-Difluoro-3-bromoanisole; Benzene, 2-bromo-1,5-difluoro-3-methoxy-; 2-Bromo-1,5-difluoro-3-methoxy-benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1,5-difluoro-3-methoxybenzene is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.