Description

2-Amino-1-(3-Bromo-Phenyl)-Ethanone is a versatile brominated aromatic ketone derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a bromo substituent, makes it a valuable precursor for constructing complex heterocyclic frameworks and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated aromatic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, photoactive materials, and advanced polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Item	Details
Product Name	2-Amino-1-(3-Bromo-Phenyl)-Ethanone
CAS No.	491837-88-8
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	1-(3-Bromophenyl)-2-aminoethanone; 2-Amino-1-(3-bromophenyl)ethanone; 3-Bromo-α-aminoacetophenone; α-Amino-3-bromoacetophenone; 2-Amino-3'-bromoacetophenone; 3'-Bromo-2-aminoacetophenone; 1-Acetyl-3-bromobenzene-2-amine; (3-Bromophenyl)(amino)methanone (tautomeric form)
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-1-(3-Bromo-Phenyl)-Ethanone is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with ICH guidelines, and we can support development projects requiring compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.