Description

Methyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propanoate is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile and stable intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and conjugated systems. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or extended aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages for bioactivity.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials, liquid crystals, and conductive polymers.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for methodology development and constructing complex molecular libraries.
• Ligand & Catalyst Preparation: Utilized in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and flavors & fragrances.

Basic Information

Item	Details
Product Name	Methyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propanoate
CAS No.	490035-82-0
Molecular Formula	C16H23BO4
Molecular Weight	290.16 g/mol
Synonyms	3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoic acid methyl ester; Methyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propionate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenepropanoic acid methyl ester; Methyl 3-(4-(pinacolatoboron)phenyl)propanoate; Methyl 4-(Pinacolatoboran)-benzenpropionat; (4-(Methoxycarbonylethyl)phenyl)boronic acid pinacol ester; CAS 490035-82-0
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Propanoate is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent hydrolysis and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.