Description

5-[(2,2,2-Trifluoroethoxy)Methyl]-2-Furoic Acid (Saltdata: Free) is a high-purity, specialized organic acid derivative featuring a furan ring core functionalized with a trifluoroethoxymethyl group. This compound is valued for its unique structural motif, which combines the aromaticity of furan with the electron-withdrawing and lipophilicity-enhancing properties of the trifluoroethoxy moiety. It serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis for research and development. Primary demand originates from the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides, leveraging the trifluoroethoxy group's ability to improve metabolic stability and bioavailability.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex molecules, heterocyclic compounds, and ligands for catalysis due to its reactive carboxylic acid and ether functionalities.
• Material Science Research: Investigated as a monomer or additive for synthesizing specialty polymers and advanced materials with specific thermal, chemical, or surface properties.
• Fluorine Chemistry Studies: Serves as a valuable substrate for studying the effects of fluorine substitution on chemical reactivity and physical properties in molecular design.

Basic Information

Product Name	5-[(2,2,2-Trifluoroethoxy)Methyl]-2-Furoic Acid (Saltdata: Free)
CAS No.	488795-29-5
Molecular Formula	C9H7F3O4
Molecular Weight	236.14 g/mol
Synonyms	2-Furoic acid, 5-[(2,2,2-trifluoroethoxy)methyl]-; 5-[(2,2,2-Trifluoroethoxy)methyl]furan-2-carboxylic acid; 5-(Trifluoroethoxymethyl)-2-furoic acid; 488795-29-5; Furan-2-carboxylic acid, 5-[(2,2,2-trifluoroethoxy)methyl]-; 5-(2,2,2-Trifluoroethoxymethyl)furan-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-[(2,2,2-Trifluoroethoxy)Methyl]-2-Furoic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices for strong acids/organic solvents. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.