Description

6(2H)-Benzofuranone,4-Ethoxyhexahydro-3A-Hydroxy-,(3Ar,4S,7Ar)-Rel-(-)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, offering precise control over molecular architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, particularly in stereoselective synthesis.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for enantioselective transformations.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance and flavor compounds requiring specific stereochemistry.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic chemistry, particularly in total synthesis and natural product chemistry projects.

Basic Information

Item	Details
Product Name	6(2H)-Benzofuranone,4-Ethoxyhexahydro-3A-Hydroxy-,(3Ar,4S,7Ar)-Rel-(-)-(9Ci)
CAS No.	488138-32-5
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	rel-(-)-4-Ethoxyhexahydro-3a-hydroxy-6(2H)-benzofuranone; (3aR,4S,7aR)-4-Ethoxyhexahydro-3a-hydroxy-6(2H)-benzofuranone; 4-Ethoxyhexahydro-3a-hydroxy-6(2H)-benzofuranone, (3aR,4S,7aR)-rel-(-)-; Hexahydro-3a-hydroxy-4-ethoxy-6(2H)-benzofuranone, rel-(-)-; Chiral Benzofuranone Derivative; 488138-32-5; 6(2H)-Benzofuranone, 4-ethoxyhexahydro-3a-hydroxy-, (3aR,4S,7aR)-rel-(-)-
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC, NMR, and specific rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent levels is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Provided on COA
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.