Description

2-(4-(Bromomethyl)Phenyl)-1,3,2-Dioxaborolane is a versatile and high-value organoboron building block, specifically a bromomethyl-substituted phenylboronic ester. Its core value proposition lies in its dual functionality, where the bromomethyl group serves as an excellent electrophilic site for alkylation or cross-coupling, and the boronic ester moiety acts as a key handle for Suzuki-Miyaura cross-coupling reactions. This makes it an indispensable intermediate for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and advanced material science, enabling the efficient construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing biaryl and substituted phenyl structures in active pharmaceutical ingredients (APIs) via Suzuki coupling.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific phenyl-boronate motifs.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating complex organic molecules used in electronic displays and lighting.
• Polymer & Resin Modification: Employed to introduce boronate ester functional groups into polymer chains for specialty materials.
• Chemical Biology & Proteomics: Utilized in the synthesis of probes and inhibitors that target specific biological pathways.
• Cross-Coupling Reactions: Primarily used in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds.
• Organic Synthesis Building Block: Acts as a versatile intermediate for further functionalization to aldehydes, alcohols, or other derivatives.

Basic Information

Product Name	2-(4-(Bromomethyl)Phenyl)-1,3,2-Dioxaborolane
CAS No.	488133-21-7
Molecular Formula	C9H10BBrO2
Molecular Weight	240.89 g/mol
Synonyms	4-(Bromomethyl)benzeneboronic acid 1,3-propanediol cyclic ester; 4-(Bromomethyl)phenylboronic acid pinacol ester (common misnomer); (4-(Bromomethyl)phenyl)boronic acid, cyclic ester with 1,3-propanediol; 2-[4-(Bromomethyl)phenyl]-1,3,2-dioxaborolane; 1,3,2-Dioxaborolane, 2-[4-(bromomethyl)phenyl]-; 4-Bromomethylbenzeneboronic acid 1,3-propanediol ester; p-(Bromomethyl)phenylboronic acid cyclic 1,3-propanediol ester
EINECS	Contact for details

Quality Control

Our 2-(4-(Bromomethyl)Phenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.