Description

5-Chloro-1-(2-Iodophenyl)-1-Oxopentane is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its aromatic and halogenated properties.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Functional Group Transformation: The reactive carbonyl and alkyl chloride groups allow for further derivatization to alcohols, amines, and other functional groups.

Basic Information

Product Name	5-Chloro-1-(2-Iodophenyl)-1-Oxopentane
CAS No.	487058-89-9
Molecular Formula	C11H12ClIO
Molecular Weight	322.57 g/mol
Synonyms	1-(2-Iodophenyl)-5-chloropentan-1-one; 5-Chloro-1-(2-iodophenyl)pentan-1-one; 2-Iodo-ω-chloroacetophenone; ω-Chloro-2-iodoacetophenone; Pentan-1-one, 5-chloro-1-(2-iodophenyl)-; 2'-Iodo-5'-chlorovalerophenone
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(2-Iodophenyl)-1-Oxopentane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.