Description

3-Chloro-5-(2-Fluorobenzylsulfinyl)-1,2,4-Thiadiazole is a specialized heterocyclic compound featuring a thiadiazole core functionalized with chloro and fluorobenzylsulfinyl groups, making it a valuable synthetic intermediate. This compound matters for its role in facilitating the development of novel active ingredients, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on the synthesis of new drug candidates, crop protection agents, and other fine chemicals where its unique sulfinyl moiety can be leveraged for further chemical transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or anti-infective targets.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, or insecticides, exploiting the bioactivity of the thiadiazole scaffold.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of advanced polymers or organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme inhibition or receptor-ligand interactions due to its electrophilic and hydrogen-bonding capabilities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	3-Chloro-5-(2-Fluorobenzylsulfinyl)-1,2,4-Thiadiazole
CAS No.	486997-72-2
Molecular Formula	C9H6ClFN2OS2
Molecular Weight	276.74 g/mol
Synonyms	3-Chloro-5-[(2-fluorophenyl)methylsulfinyl]-1,2,4-thiadiazole; 1,2,4-Thiadiazole, 3-chloro-5-[(2-fluorophenyl)methylsulfinyl]-; 3-Chloro-5-(2-fluorobenzylsulfinyl)-1,2,4-thiadiazole; (2-Fluorobenzyl)sulfinyl-3-chloro-1,2,4-thiadiazole; 5-(2-Fluorobenzylsulfinyl)-3-chloro-1,2,4-thiadiazole
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(2-Fluorobenzylsulfinyl)-1,2,4-Thiadiazole is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere if opened for prolonged periods. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.