Description

4-(N,N-Dimethylsulphonamido)Benzeneboronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound is valued for its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a dimethylsulfonamido moiety that can influence solubility and serve as a synthetic handle. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring aryl-boronic acid coupling steps.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl halides in the presence of a palladium catalyst.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate sulfonamide and aryl motifs.
• Material Science Precursor: Potential monomer or functionalizing agent for creating advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological systems and enzyme inhibition.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry programs.

Basic Information

Product Name	4-(N,N-Dimethylsulphonamido)Benzeneboronic Acid
CAS No.	486422-59-7
Molecular Formula	C8H12BNO4S
Molecular Weight	229.06 g/mol
Synonyms	4-(Dimethylsulfamoyl)phenylboronic acid; [4-(Dimethylsulfamoyl)phenyl]boronic acid; N,N-Dimethyl-4-boronobenzenesulfonamide; B-[4-(Dimethylsulfamoyl)phenyl]boronic acid; 4-Borono-N,N-dimethylbenzenesulfonamide; p-(N,N-Dimethylsulfamoyl)phenylboronic acid; 4-(Dimethylsulfonylamino)benzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(N,N-Dimethylsulphonamido)Benzeneboronic Acid is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.