Description

Benzenesulfonamide-3-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing sulfonamide and biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and biochemical tools for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for CROs and CDMOs offering bespoke chemical synthesis services to global clients.
• Academic Research: Used in university and institutional labs for methodological development in synthetic organic chemistry and catalysis.

Basic Information

Item	Details
Product Name	Benzenesulfonamide-3-Boronic Acid Pinacol Ester
CAS No.	486422-08-6
Molecular Formula	C18H20BNO4S
Molecular Weight	357.23 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide; Benzenesulfonamide, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Borono-benzenesulfonamide pinacol ester; 3-Sulfamoylphenylboronic acid pinacol ester; B-(3-Sulfamoylphenyl)boronic acid pinacol ester; 486422-08-6; AS-15749; SCHEMBL218062
EINECS	Contact for details

Quality Control

Every batch of Benzenesulfonamide-3-Boronic Acid Pinacol Ester is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.