Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Fluoride, 2-Fluoro- (9Ci) is a specialized fluorinated building block derived from norbornene, offering a unique combination of strained bicyclic structure and a reactive carbonyl fluoride group. This compound is valued for its role in advanced organic synthesis, particularly in the development of novel pharmaceuticals, agrochemicals, and functional materials where the introduction of fluorine atoms is critical. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for introducing the fluorinated norbornyl moiety into active pharmaceutical ingredients (APIs), potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorinated structure can improve efficacy and environmental profile.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers, coatings, and resins with tailored thermal and chemical resistance properties.
• Fluorination Reagent: Employed in organic synthesis as a source of the carbonyl fluoride group for acyl fluoridation reactions under controlled conditions.
• Ligand and Catalyst Development: Utilized as a precursor for creating novel chiral ligands or organometallic catalysts used in asymmetric synthesis.
• Academic and Industrial R&D: A valuable tool for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Fluoride, 2-Fluoro- (9Ci)
CAS No.	484649-06-1
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	2-Fluoro-2-norbornenecarbonyl fluoride; 5-Norbornene-2-carbonyl fluoride, 2-fluoro-; 2-Fluoronorborn-5-ene-2-carbonyl fluoride; Bicyclo[2.2.1]hept-5-ene-2-carbonyl fluoride, 2-fluoro-; 2-Fluoro-5-norbornenecarbonyl fluoride; 2-Fluoro-2-bicyclo[2.2.1]hept-5-enecarbonyl fluoride; 2-Fluoro-2-norbornene-5-carbonyl fluoride; 2-Fluoro-2-(bicyclo[2.2.1]hept-5-en-2-yl)carbonyl fluoride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carbonyl Fluoride, 2-Fluoro- (9Ci) is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer requirements or internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and highly volatile nature, this material should be stored in a cool, dry, and well-ventilated area, ideally at controlled room temperature (15-25°C). The container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture uptake and decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.