Description

Rac-tert-Butyl 2-(1-Benzofuran-2-Ylcarbonyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound serves as a critical building block for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of central nervous system (CNS) and metabolic disorder therapeutics. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient production of target molecules under GMP-like conditions.
• Reference Standard: Serves as an analytical standard for quality control and method validation in API manufacturing.
• Academic & Institutional Research: Utilized in synthetic organic chemistry studies exploring novel heterocyclic compounds and reaction methodologies.

Basic Information

Product Name	Rac-tert-Butyl 2-(1-Benzofuran-2-Ylcarbonyl)Piperidine-1-Carboxylate
CAS No.	483281-42-1
Molecular Formula	C19H23NO4
Molecular Weight	329.39 g/mol
Synonyms	1-Boc-2-(benzofuran-2-carbonyl)piperidine; tert-Butyl 2-(1-benzofuran-2-carbonyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-(2-benzofuranylcarbonyl)piperidine; 2-(1-Benzofuran-2-ylcarbonyl)-1-(tert-butoxycarbonyl)piperidine; Piperidine-1-carboxylic acid, 2-(1-benzofuran-2-ylcarbonyl)-, 1,1-dimethylethyl ester; 483281-42-1; 1,1-Dimethylethyl 2-(1-benzofuran-2-ylcarbonyl)-1-piperidinecarboxylate
EINECS	Contact for details

Quality Control

Our Rac-tert-Butyl 2-(1-Benzofuran-2-Ylcarbonyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.